Detalhe da pesquisa
1.
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains.
Cell
; 180(4): 633-644.e12, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32032505
2.
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains.
Cell
; 184(25): 6207-6210, 2021 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34890553
3.
Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation.
Mol Cell
; 76(1): 126-137.e7, 2019 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31444107
4.
Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity.
PLoS Genet
; 19(5): e1010760, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37200393
5.
Systemic proteome phenotypes reveal defective metabolic flexibility in Mecp2 mutants.
Hum Mol Genet
; 33(1): 12-32, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37712894
6.
Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer's Disease.
Mol Cell Proteomics
; 22(5): 100542, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37024090
7.
Cellular Proteomic Profiling Using Proximity Labeling by TurboID-NES in Microglial and Neuronal Cell Lines.
Mol Cell Proteomics
; 22(6): 100546, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37061046
8.
DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining.
Nucleic Acids Res
; 51(15): 7972-7987, 2023 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37395399
9.
Signatures of glial activity can be detected in the CSF proteome.
Proc Natl Acad Sci U S A
; 119(24): e2119804119, 2022 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35666874
10.
Cross-Platform Synaptic Network Analysis of Human Entorhinal Cortex Identifies TWF2 as a Modulator of Dendritic Spine Length.
J Neurosci
; 43(20): 3764-3785, 2023 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37055180
11.
Genetic control of the human brain proteome.
Am J Hum Genet
; 108(3): 400-410, 2021 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33571421
12.
Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains.
Acta Neuropathol
; 147(1): 29, 2024 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38308693
13.
Prospective direct comparison of biologic treatments for severe eosinophilic asthma: Findings from the PRISM study.
Ann Allergy Asthma Immunol
; 132(4): 457-462.e2, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37977324
14.
Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation.
Cell
; 137(1): 133-45, 2009 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19345192
15.
Predictors of Early and Late Lung Function Improvement in Severe Eosinophilic Asthma on Type2-Biologics in the PRISM Study.
Lung
; 202(1): 41-51, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38252134
16.
Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons.
Alzheimers Dement
; 20(4): 2952-2967, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38470006
17.
Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid.
Alzheimers Dement
; 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38713744
18.
Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment.
Neurobiol Dis
; 186: 106286, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37689213
19.
Integrating human brain proteomes with genome-wide association data implicates novel proteins in post-traumatic stress disorder.
Mol Psychiatry
; 27(7): 3075-3084, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35449297
20.
APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer's pathology in trisomy 21 neurons.
Mol Psychiatry
; 27(4): 1970-1989, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35194165